What is a human insulin analogue

In a sense, human insulin analogue, is not the true sense of the insulin, but its diabetes insulin treatment were upgraded to a new level. The hypoglycemic effect of human insulin analogues and human insulin is comparable to, and some of its characteristics and even more in line with the physiological requirements of the human body than human insulin.
At present, human insulin analogue is divided into the following two:
A long-acting human insulin analogues
Traditional, long-acting insulin (NPH, PZI, etc.) will appear after subcutaneous injection of the peak blood concentration, coupled with drug absorption is not stable enough, it is difficult to provide a relatively stable, close to the physiological state of basal insulin levels. At present, long-acting human insulin analogues (such as Lantus) characteristics of drug absorption, stability, and no obvious peak can simulate the physiological basis of insulin secretion, lasting efficacy, once daily injection, the effect can be maintained for 24 hours every day at any time injection (as long as daily injection time is relatively fixed to).
2, available human insulin analogues
The main features of the available human insulin analogues: (1) onset of fast, 15 minutes after subcutaneous injection of onset; ② peak quickly after injection of 30 to 60 minutes to reach the pharmacodynamic peak coincided with the postprandial glucose peak time match control of postprandial blood glucose effect; the ③ efficacy to maintain a short time, about three hours (2-4 hours).