Saturday 14 July 2012

What are causes the high creatinine of diabetic nephropathy


When it comes to diabetic nephropathy, we all know, diabetic nephropathy is the most serious diabetes complications, diabetic nephropathy appears creatinine increased more than the pathological symptoms of diabetic nephropathy in patients with the disease gradually increasing embodied. Elevated serum creatinine, indicating kidney serious injury.
Serum creatinine is a product of the metabolism of human muscle. Exogenous creatinine intake of stability, in vivo formation constant (daily 20mg/kg), serum creatinine concentration depends on the glomerular filtration function. But serum creatinine and creatinine clearance rate is not completely consistent and the creatinine clearance, serum creatinine is more sensitive. Renal dysfunction early (decompensated), serum creatinine, creatinine clearance rate was normal.
What are the high creatinine of diabetic nephropathy reasons? When the diabetic kidney damage, glomerular filtration rate decreased more than 50% of the normal, serum creatinine began to rapidly rise, therefore, when the diabetic serum creatinine rise is obviously higher than normal, often renal function has seriously damaged. Creatinine clearance by glomerular enrichment function, in the case of impaired renal concentration, serum creatinine is a reflection of the most reliable indicator of glomerular function, but also reflect the indicators of renal function in diabetes. Normal male serum creatinine for the 53 ~ 106gmol / L, for women 44.2 ~ 97.2gmol / L.
Diabetic nephropathy can cure? 】 The traditional treatment is often directly aimed at the elimination of proteinuria to start treatment, not the root cause for the cause of proteinuria. That is the focus of the treatment on the repair of the epithelial cells and mesangial cells. A truly effective treatment measures should be integrated use of vasodilators, anti-inflammatory, anticoagulant and degradation of harmful substances, the use of drugs is not just a simple use of Chinese and Western medicines for individual treatment, and to keep the Western medicine treatment means of the increase in Chinese medicine based on treatment intensity, and a new combination of methods, such treatment will be very different. This method is called: micro-based medicine blocking renal fibrosis infiltration method.
Practice has proved that this treatment can be determined by the exact effect of the repair of the glomerular capillary epithelial cells: damage epithelial cells and mesangial cell function been fixed, the condition will get better, "disease", since improved epithelial cell function will be restored, restore the function, proteinuria will naturally disappear. This function after the resumption of proteinuria disappeared, then the probability of recurrence will reduce. Disease like a natural!