Type 1 diabetes is a serious threat to the physical and mental health of children and young people's development, so understand the predisposing factors of type 1 diabetes is particularly important to do preventive work. So, what factors will lead to type 1 diabetes?
1.own immune system defects: to detect a variety of autoimmune antibodies in the blood of patients with type I diabetes, such as glutamic acid decarboxylase (GAD), islet cell antibodies (ICA antibodies). These abnormal autoantibodies can damage human islet insulin secretion from B cells, not normal insulin secretion.
2. Viral infections may be contributory factors: Many scientists suspect the virus can also cause type I diabetes. This is because the type I diabetic patients before the onset of a period of time is often too viral infection, and type I diabetes epidemic, often appear after the virus is endemic. Viruses, such as the viruses that cause mumps and rubella, and polio can cause the Coxsackie virus family, can play a role in type I diabetes.
3. genetic factors: The current study suggests that a genetic defect is the basis of the incidence of type I diabetes, this genetic defect is manifested in the sixth HLA antigens on chromosome abnormalities. Scientist's research suggests that: I diabetic characteristics of familial incidence, if the parents have diabetes, and then compared with no such family history people are more susceptible to the disease.
